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mTOR Associated Protein, LST8 Homolog MeSH Descriptor Data 2023


MeSH Heading
mTOR Associated Protein, LST8 Homolog
Tree Number(s)
D05.500.337.250
D08.811.913.696.620.682.700.931.500.250
D12.644.360.024.310
D12.776.157.057.073
D12.776.476.024.389
D12.776.476.563.931.500.250
Unique ID
D000076242
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000076242
Scope Note
An adaptor protein, consisting of seven WD REPEATS along its length, that functions as a component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 and mTORC2 COMPLEX. It interacts directly with mTOR to enhance its kinase activity and stabilizes the mTOR-RPTOR PROTEIN interaction in nutrient-poor conditions, favoring RPTOR inhibition of mTOR activity.
Entry Term(s)
G protein beta Subunit-like Polypeptide
GBetaL Protein
mLST8 Protein
Registry Number
0
Previous Indexing
Adaptor Proteins, Signal Transducing (2013-2017)
Proteins (2011-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2021/05/21
mTOR Associated Protein, LST8 Homolog Preferred
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