MeSH Browser

MeSH Heading: A Kinase Anchor Proteins
Tree Number(s): D12.644.360.024.065; D12.776.157.057.003; D12.776.476.024.069
Unique ID: D054758
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054758
Scope Note: A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA.
Entry Term(s): A-Kinase Anchor Proteins; A-Kinase Anchoring Protein; A-Kinase Anchoring Proteins; Protein Kinase A Anchor Proteins
Public MeSH Note: 2008
History Note: 2008
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2020/01/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0507519
Scope Note: A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA.
Terms: A Kinase Anchor Proteins Preferred Term
Term UI T693300
Date03/09/2007
LexicalTag NON
ThesaurusID NLM (2008); A-Kinase Anchoring Protein
Term UI T000999138
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021); A-Kinase Anchoring Proteins
Term UI T000999139
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021); A-Kinase Anchor Proteins
Term UI T696085
Date04/23/2007
LexicalTag NON
ThesaurusID NLM (2008); Protein Kinase A Anchor Proteins
Term UI T696086
Date04/23/2007
LexicalTag NON
ThesaurusID NLM (2008)

A Kinase Anchor Proteins MeSH Descriptor Data 2025