MeSH Browser

MeSH Heading: Myeloid Differentiation Factor 88
Tree Number(s): D12.644.360.024.311; D12.776.157.057.074; D12.776.476.024.390
Unique ID: D053594
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053594
Scope Note: An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
Entry Term(s): MyD88 Protein; TLR Signal Adaptor Protein MyD88; Toll-Like Receptor Signal Adaptor Protein MyD88
Registry Numbers: 0
Public MeSH Note: 2007; MYELOID DIFFERENTIATION FACTOR 88 was indexed under ADAPTOR PROTEINS, SIGNAL TRANSDUCING 2006, under ANTIGENS, DIFFERENTIATION & RECEPTORS, IMMUNOLOGIC 2000-2006, & under PROTEINS 1990-1999
History Note: 2007(1990)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/03/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0178953
Registry Numbers: 0
Scope Note: An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
Terms: Myeloid Differentiation Factor 88 Preferred Term
Term UI T636300
Date04/12/2005
LexicalTag NON
ThesaurusID NLM (2007); MyD88 Protein
Term UI T208958
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); TLR Signal Adaptor Protein MyD88
Term UI T542271
Date06/03/2003
LexicalTag ABX
ThesaurusID NLM (2007); Toll-Like Receptor Signal Adaptor Protein MyD88
Term UI T666170
Date02/10/2006
LexicalTag NON
ThesaurusID NLM (2007)

Myeloid Differentiation Factor 88 MeSH Descriptor Data 2025