- Concept UI
- M0493409
- Registry Numbers
- 0
- Scope Note
- A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM.
- Terms
-
Nod1 Signaling Adaptor Protein
Preferred Term
Term UI
T663324
Date12/28/2005
LexicalTag
ABX
ThesaurusID
NLM (2007)
-
CARD4 Protein
Term UI
T663325
Date12/28/2005
LexicalTag
ABX
ThesaurusID
NLM (2007)
-
Caspase Recruitment Domain Protein 4
Term UI
T663326
Date12/28/2005
LexicalTag
NON
ThesaurusID
NLM (2007)
-
Nucleotide Oligomerization Domain 1 Protein
Term UI
T663327
Date12/28/2005
LexicalTag
NON
ThesaurusID
NLM (2007)