MeSH Browser

MeSH Heading: cdc25 Phosphatases
Tree Number(s): D08.811.277.352.650.625.225.100; D08.811.277.352.650.775.250.100; D08.811.641.755.100; D12.776.167.100; D12.776.476.559.225.100; D12.776.476.564.250.100
Unique ID: D020687
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020687
Annotation: do not confuse with CDC25 GUANINE NUCLEOTIDE EXCHANGE FACTOR
Scope Note: A subclass of dual specificity phosphatases that play a role in the progression of the CELL CYCLE. They dephosphorylate and activate CYCLIN-DEPENDENT KINASES.
Entry Term(s): Cell Division Cycle 25B protein; Dual Specificity Phosphatase Cdc25A; Dual Specificity Phosphatase Cdc25B; Dual Specificity Phosphatase Cdc25C; M-Phase Inducer Phosphatase 1; M-Phase Inducer Phosphatase 2; M-Phase Inducer Phosphatase 3; cdc25 Phosphatase; cdc25A Phosphatase; cdc25B Phosphatase; cdc25C Phosphatase
Related Numbers: EC 3.1.3.16; EC 3.1.3.48
Previous Indexing: Cell Cycle Proteins (1996-1999); Phosphoprotein Phosphatase (1996-1999)
Public MeSH Note: 2008; see CDC25 PHOSPHATASE 2000-2008; CDC25 PROTEIN (now CDC25 PHOSPHATASE) was indexed under CELL CYCLE PROTEINS 1995-1999 & PHOSPHOPROTEIN PHOSPHATASES 1996-1999; CDC25A PHOSPHATASE & CDC25B PHOSPHATASE were indexed under CDC25 PHOSPHATASES 1999-2007; CDC25C PHOSPHATASE was indexed under CDC25 PHOSPHATASES & CELL CYCLE PROTEINS 2000-2007, under PHOSPHOPROTEIN PHOSPHATASE 1996-1999 & under PROTEINS 1993-1995
History Note: 2008(1995)
Date Established: 2000/01/01
Date of Entry: 1999/11/08
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Phosphoric Monoester Hydrolases [D08.811.277.352.650]
        
        Phosphoprotein Phosphatases [D08.811.277.352.650.625]
        
        Dual-Specificity Phosphatases [D08.811.277.352.650.625.225]
        
        cdc25 Phosphatases [D08.811.277.352.650.625.225.100]
        
        Dual Specificity Phosphatase 1 [D08.811.277.352.650.625.225.200]
        
        Dual Specificity Phosphatase 2 [D08.811.277.352.650.625.225.250]
        
        Dual Specificity Phosphatase 3 [D08.811.277.352.650.625.225.300]
        
        Dual Specificity Phosphatase 6 [D08.811.277.352.650.625.225.600]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Phosphoric Monoester Hydrolases [D08.811.277.352.650]
        
        Protein Tyrosine Phosphatases [D08.811.277.352.650.775]
        
        Dual-Specificity Phosphatases [D08.811.277.352.650.775.250]
        
        cdc25 Phosphatases [D08.811.277.352.650.775.250.100]
        
        Dual Specificity Phosphatase 1 [D08.811.277.352.650.775.250.200]
        
        Dual Specificity Phosphatase 2 [D08.811.277.352.650.775.250.250]
        
        Dual Specificity Phosphatase 3 [D08.811.277.352.650.775.250.300]
        
        Dual Specificity Phosphatase 6 [D08.811.277.352.650.775.250.600]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Multifunctional Enzymes [D08.811.641]
    - Dual-Specificity Phosphatases [D08.811.641.755]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Cell Cycle Proteins [D12.776.167]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Phosphoprotein Phosphatases [D12.776.476.559]
      - Dual-Specificity Phosphatases [D12.776.476.559.225]
        
        cdc25 Phosphatases [D12.776.476.559.225.100]
        
        Dual Specificity Phosphatase 1 [D12.776.476.559.225.200]
        
        Dual Specificity Phosphatase 2 [D12.776.476.559.225.250]
        
        Dual Specificity Phosphatase 3 [D12.776.476.559.225.300]
        
        Dual Specificity Phosphatase 6 [D12.776.476.559.225.600]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Protein Tyrosine Phosphatases [D12.776.476.564]
      - Dual-Specificity Phosphatases [D12.776.476.564.250]
        
        cdc25 Phosphatases [D12.776.476.564.250.100]
        
        Dual Specificity Phosphatase 1 [D12.776.476.564.250.200]
        
        Dual Specificity Phosphatase 2 [D12.776.476.564.250.250]
        
        Dual Specificity Phosphatase 3 [D12.776.476.564.250.300]
        
        Dual Specificity Phosphatase 6 [D12.776.476.564.250.600]

cdc25 Phosphatases Preferred

cdc25C Phosphatase Narrower

cdc25B Phosphatase Narrower

Concept UI: M0267828
Terms: cdc25B Phosphatase Preferred Term
Term UI T297830
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); Cell Division Cycle 25B protein
Term UI T638292
Date04/28/2005
LexicalTag NON
ThesaurusID NLM (2008); M-Phase Inducer Phosphatase 2
Term UI T691307
Date02/08/2007
LexicalTag NON
ThesaurusID NLM (2008); Dual Specificity Phosphatase Cdc25B
Term UI T691308
Date02/08/2007
LexicalTag ABX
ThesaurusID NLM (2008)

cdc25A Phosphatase Narrower

cdc25 Phosphatases MeSH Descriptor Data 2025