MeSH Browser

MeSH Heading: Survivin
Tree Number(s): D12.644.360.075.437.625; D12.776.167.576; D12.776.220.600.450.495; D12.776.476.075.437.625
Unique ID: D000077022
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077022
Scope Note: An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.
Entry Term(s): BIRC5 Protein; Baculoviral IAP Repeat-containing Protein 5
Previous Indexing: Inhibitor of Apoptosis Proteins (2012-2018); Microtubule-Associated Proteins (1997-2018); Neoplasm Proteins (1997-2018)
Public MeSH Note: 2019
History Note: 2019
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/01/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000639155
Scope Note: An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.
Terms: Survivin Preferred Term
Term UI T000936409
Date11/21/2017
LexicalTag NON
ThesaurusID NLM (2019); Baculoviral IAP Repeat-containing Protein 5
Term UI T000936410
Date11/21/2017
LexicalTag ABX
ThesaurusID NLM (2019); BIRC5 Protein
Term UI T000936411
Date11/21/2017
LexicalTag ACX
ThesaurusID NLM (2019)

Survivin MeSH Descriptor Data 2025