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KRIT1 Protein MeSH Descriptor Data 2026


MeSH Heading
KRIT1 Protein
Tree Number(s)
D12.776.220.600.450.458
D12.776.624.664.700.119
D12.776.631.560.465
Unique ID
D000075927
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000075927
Scope Note
A microtubule-associated protein consisting of four ANKYRIN REPEATS and a C-terminal FERM DOMAIN. It links the CYTOSKELETON to CELL JUNCTIONS via integrin cytoplasmic domain-associated protein-1 and plays an important role in regulating cell proliferation and integrity of endothelial cell junctions. It is also involved in REACTIVE OXYGEN SPECIES metabolism. Mutations in the KRIT1 gene are associated with type I CEREBRAL CAVERNOUS MALFORMATIONS.
Entry Term(s)
Cerebral Cavernous Malformations 1 Protein
Krev Interaction Trapped Protein 1
Registry Numbers
0
Previous Indexing
Microtubule-Associated Proteins (1997-2017)
Proto-Oncogene Proteins (1997-2017)
Public MeSH Note
2018
History Note
2018
Date Introduced
2018/01/01
Last Updated
2018/01/01
KRIT1 Protein Preferred
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