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Proto-Oncogene Proteins c-met MeSH Descriptor Data 2023


MeSH Heading
Proto-Oncogene Proteins c-met
Tree Number(s)
D08.811.913.696.620.682.725.400.075
D12.776.476.568.400.075
D12.776.543.750.630.186
D12.776.543.750.750.400.100
D12.776.624.664.700.186
Unique ID
D019859
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019859
Scope Note
Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia.
Entry Term(s)
HGF Receptor
Hepatocyte Growth Factor Receptor
MET Proto-Oncogene, Receptor Tyrosine Kinase
MET Receptor Tyrosine Kinase
Receptor, HGF
Receptor, Hepatocyte Growth Factor
Receptor, Scatter Factor
Scatter Factor Receptor
c-Met Receptor Tyrosine Kinase
c-met Proteins
met Proto-Oncogene Proteins
Registry Number
EC 2.7.10.1
Public MeSH Note
2006; see PROTO-ONCOGENE PROTEIN C-MET 2000-2005, see PROTO-ONCOGENE PROTEINS C-MET 1998-1999; PROTO-ONCOGENE PROTEIN C-MET was indexed under RECEPTOR PROTEIN-TYROSINE KINASE 1994-1997 & PROTO-ONCOGENE PROTEINS 1989-1993
History Note
2006, 1998-1999
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2021/05/21
Proto-Oncogene Proteins c-met Preferred
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