- Concept UI
- M0533994
- Registry Numbers
- EC 2.7.10.1
- Related Numbers
- EC 2.7.10.1
- Scope Note
- A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects.
- Terms
-
Receptor Tyrosine Kinase-like Orphan Receptors
Preferred Term
Term UI
T748078
Date03/25/2009
LexicalTag
NON
ThesaurusID
NLM (2010)
-
Neurotrophic Tyrosine Kinase, Receptor-related Proteins
Term UI
T748080
Date03/25/2009
LexicalTag
NON
ThesaurusID
NLM (2010)
-
NTRKR Receptors
Term UI
T748081
Date03/25/2009
LexicalTag
ABX
ThesaurusID
NLM (2010)
-
Receptor Tyrosine Kinase-like Orphan Receptor
Term UI
T001089426
Date10/06/2020
LexicalTag
NON
ThesaurusID
NLM (2022)
-
ROR Tyrosine Kinase Receptors
Term UI
T748079
Date03/25/2009
LexicalTag
ABX
ThesaurusID
NLM (2010)