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Discoidin Domain Receptors MeSH Descriptor Data 2023


MeSH Heading
Discoidin Domain Receptors
Tree Number(s)
D08.811.913.696.620.682.725.400.005
D12.776.476.568.400.005
D12.776.543.750.630.005
D12.776.543.750.685.050
D12.776.543.750.705.880.300
Unique ID
D000070818
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000070818
Scope Note
Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.
Entry Term(s)
DDR Proteins
Discoidin Domain Receptor
Registry Number
EC 2.7.10.1
Public MeSH Note
2017; DISCOIDIN DOMAIN RECEPTORS was indexed under RECEPTORS, MITOGEN and RECEPTOR PROTEIN-TYROSINE KINASES 1999-2016
History Note
2017 (1999)
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2021/05/21
Discoidin Domain Receptors Preferred
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