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A BCL-2-like protein that has a C-terminal BCL-2 homology (BH3) domain and forms heterodimers with other BCL-2 FAMILY PROTEINS. It is a strong inducer of APOPTOSIS and ANOIKIS; several isoforms are expressed (BimEL, Bim L, Bim-alpha, Bim-s; and Bim-gamma) that have different potencies for inducing apoptosis.
Entry Term(s)
BCL2L11 Protein
BIM Protein
Bcl-2-Binding Protein, BIM
Bcl-2-Interacting Mediator of Cell Death
Registry Numbers
0
Public MeSH Note
2017; BCL-2-LIKE PROTEIN 11 was indexed under MEMBRANE PROTEINS; PROTO-ONCOGENE PROTEINS; APOPTOSIS REGULATORY PROTEINS 2005-2016; and under CARRIER PROTEINS 1998-2005
A BCL-2-like protein that has a C-terminal BCL-2 homology (BH3) domain and forms heterodimers with other BCL-2 FAMILY PROTEINS. It is a strong inducer of APOPTOSIS and ANOIKIS; several isoforms are expressed (BimEL, Bim L, Bim-alpha, Bim-s; and Bim-gamma) that have different potencies for inducing apoptosis.