NLM Logo

Beclin-1 MeSH Descriptor Data 2022


MeSH Heading
Beclin-1
Tree Number(s)
D12.644.360.075.335
D12.776.094.500
D12.776.476.075.335
Unique ID
D000071186
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071186
Scope Note
An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.
Entry Term(s)
ATG-6 Protein
ATG6 Protein
Beclin-1 Protein
Beclin1
Coiled-coil Myosin-like Bcl2-interacting Protein
GT197 Protein
Registry Number
0
Previous Indexing
Apoptosis Regulatory Proteins (2006-2016)
Membrane Proteins (2006-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/03/01
Beclin-1 Preferred
page delivered in 0.181s