MeSH Browser

MeSH Heading: Autophagy-Related Protein 5
Tree Number(s): D12.776.094.250
Unique ID: D000071187
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071187
Scope Note: An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
Entry Term(s): ATG-5 Protein; ATG5 Protein; Apoptosis-Specific Protein; Autophagy Protein-5; Autophagy-Related 5 Protein
Previous Indexing: Microtubule-Associated Proteins (2004-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/02/25

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000613472
Scope Note: An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
Terms: Autophagy-Related Protein 5 Preferred Term
Term UI T000895942
Date02/25/2016
LexicalTag NON
ThesaurusID NLM (2017); Autophagy Protein-5
Term UI T000893480
Date01/11/2016
LexicalTag NON
ThesaurusID NLM (2017); Autophagy-Related 5 Protein
Term UI T000893482
Date01/11/2016
LexicalTag NON
ThesaurusID NLM (2017); ATG5 Protein
Term UI T000893483
Date01/11/2016
LexicalTag ABX
ThesaurusID NLM (2017); ATG-5 Protein
Term UI T000893484
Date01/11/2016
LexicalTag NON
ThesaurusID NLM (2017); Apoptosis-Specific Protein
Term UI T000893485
Date01/11/2016
LexicalTag NON
ThesaurusID NLM (2017)

Autophagy-Related Protein 5 MeSH Descriptor Data 2025