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Autophagy-Related Protein 5 MeSH Descriptor Data 2025


MeSH Heading
Autophagy-Related Protein 5
Tree Number(s)
D12.776.094.250
Unique ID
D000071187
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071187
Scope Note
An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
Entry Term(s)
ATG-5 Protein
ATG5 Protein
Apoptosis-Specific Protein
Autophagy Protein-5
Autophagy-Related 5 Protein
Previous Indexing
Microtubule-Associated Proteins (2004-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/02/25
Autophagy-Related Protein 5 Preferred
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