An autocrine growth factor and mitogen for a broad range of target cells including EPITHELIAL CELLS; FIBROBLASTS and immune cells. It occurs as a membrane-bound protein that can be cleaved to release an active secreted form.
Entry Term(s)
Schwannoma-derived Growth Factor
Public MeSH Note
2015; AMPHIREGULIN was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 1988-2014
An autocrine growth factor and mitogen for a broad range of target cells including EPITHELIAL CELLS; FIBROBLASTS and immune cells. It occurs as a membrane-bound protein that can be cleaved to release an active secreted form.