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Heparin-binding EGF-like Growth Factor MeSH Descriptor Data 2023


MeSH Heading
Heparin-binding EGF-like Growth Factor
Tree Number(s)
D12.644.276.382.625
D12.776.467.382.625
D23.529.382.625
Unique ID
D066257
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D066257
Scope Note
An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells.
Entry Term(s)
Diphtheria Toxin Receptor
Diphtheria Toxin Receptors
HB-EGF
HB-EGF Precursor
Heparin-binding EGF-like Growth-Factor
Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein
Receptor, Diphtheria Toxin
SF HB-EGF
Short Form HB-EGF
Registry Number
0
Public MeSH Note
2015; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 2008-2014, and under EPIDERMAL GROWTH FACTOR 1992-2007
History Note
2015
Date Established
2015/01/01
Date of Entry
2014/06/26
Revision Date
2014/06/24
Heparin-binding EGF-like Growth Factor Preferred
Short Form HB-EGF Narrower
Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein Narrower
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