- Concept UI
- M0234074
- Scope Note
- A multiprotein complex that functions as a peptide hydrolase, or isopeptidase to cleave NEDD8 PROTEIN from the CULLIN and UBIQUITIN-PROTEIN LIGASES, controlling the activity of the ligases. It is highly conserved in eukaryotes and typically consists of 8 subunits (CSN 1-8 proteins). The COP9 signalosome was originally identified in plants, where it controls gene transcription in response to light.
- Terms
-
COP9 Signalosome Complex
Preferred Term
Term UI
T000923450
Date05/05/2017
LexicalTag
ABX
ThesaurusID
NLM (2005)
-
COP9 Signalosome (CSN)
Term UI
T644148
Date06/24/2005
LexicalTag
ACX
ThesaurusID
NLM (2005)
-
COP9 Signalsome
Term UI
T000926422
Date06/08/2017
LexicalTag
ABX
ThesaurusID
NLM (2018)
-
Constitutive Photomorphogenesis 9 Signalsome
Term UI
T000926423
Date06/08/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
Constitutive Photomorphogenesis 9 Signalosome
Term UI
T000923449
Date05/05/2017
LexicalTag
NON
ThesaurusID
NLM (2018)