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NEDD8 Protein MeSH Descriptor Data 2023


MeSH Heading
NEDD8 Protein
Tree Number(s)
D12.776.947.218
Unique ID
D000075687
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000075687
Scope Note
A ubiquitin-like protein that functions in CELL CYCLE regulation and embryogenesis. It is attached covalently to its substrates following activation by the UBIQUITIN-ACTIVATING ENZYME E1-UBA3 enzyme complex. NEDD8 attaches to CULLINS, activating their E3 UBIQUITIN LIGASE activity, to promote polyubiquitination and degradation of CYCLINS and regulatory proteins
Entry Term(s)
NEDD-8 Protein
Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8
Ubiquitin-like Protein NEDD8
Registry Number
0
Previous Indexing
Ubiquitins (1993-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/06/29
NEDD8 Protein Preferred
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