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Mitochondrial Permeability Transition Pore MeSH Descriptor Data 2023


MeSH Heading
Mitochondrial Permeability Transition Pore
Tree Number(s)
D05.500.437
D12.776.543.585.475.563
D12.776.575.750.563
Unique ID
D000083162
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000083162
Scope Note
A multiprotein inner mitochondrial complex which opens only under certain pathological conditions (e.g., OXIDATIVE STRESS) uncoupling the membrane leading to APOPTOSIS and MITOCHONDRIAL TRANSMEMBRANE PERMEABILITY-DRIVEN NECROSIS particularly in CARDIOMYOCYTES during MYOCARDIAL REPERFUSION INJURY.
Entry Term(s)
Mitochondrial Megachannel
Mitochondrial Permeability Transition Pore (mPTP)
mPTP Protein
Registry Number
0
Public MeSH Note
Mitochondrial Permeability Transition Pore was indexed under MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS 2007-2020; ION CHANNELS 2003-2006; MEMBRANE PROTEINS 1999-2002; CYCLOSPORINS 1999-2000
History Note
2021(1999)
Date Established
2021/01/01
Date of Entry
2020/07/07
Revision Date
2020/02/21
Mitochondrial Permeability Transition Pore Preferred
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