MeSH Browser

MeSH Heading: Inflammasomes
Tree Number(s): D05.500.224
Unique ID: D058847
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D058847
Scope Note: Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.
Entry Term(s): Inflammasome; Pyroptosome; Pyroptosomes
See Also: Immunity, Innate; Inflammation Mediators; NLR Family, Pyrin Domain-Containing 3 Protein
Public MeSH Note: 2011
History Note: 2011
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Revision Date: 2017/02/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0544941
Scope Note: Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.
Terms: Inflammasomes Preferred Term
Term UI T768193
Date03/29/2010
LexicalTag NON
ThesaurusID NLM (2011); Inflammasome
Term UI T000879388
Date05/07/2015
LexicalTag NON
ThesaurusID NLM (2016); Pyroptosome
Term UI T000880022
Date05/20/2015
LexicalTag NON
ThesaurusID NLM (2016); Pyroptosomes
Term UI T000880024
Date05/20/2015
LexicalTag NON
ThesaurusID NLM (2016)

Inflammasomes MeSH Descriptor Data 2025