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Ubiquitin-Specific Peptidase 7 MeSH Descriptor Data 2022


MeSH Heading
Ubiquitin-Specific Peptidase 7
Tree Number(s)
D08.811.037.750.750
D08.811.277.656.300.887.875
Unique ID
D000076084
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000076084
Scope Note
A ubiquitinyl hydrolase that deubiquitinates several proteins with critical roles in DNA REPAIR, cell growth, and survival, including TUMOR SUPPRESSOR PROTEIN P53; MDM-2 PROTEIN; and PTEN PHOSPHOHYDROLASE. It also stabilizes herpesvirus 1 trans-acting transcriptional protein VMW110 during HSV-1 infection, contributing to its function as a TRANS-ACTIVATOR.
Entry Term(s)
HAUSP Protein
Herpesvirus-Associated Ubiquitin-Specific Peptidase
USP7 Protein
Registry Number
EC 3.4.19.12
Previous Indexing
Endopeptidases (2002-2017)
Ubiquitin Thiolesterase (2008-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2021/05/10
Ubiquitin-Specific Peptidase 7 Preferred
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