MeSH Browser

MeSH Heading: Ataxin-7
Tree Number(s): D12.776.631.069.901; D12.776.660.075.900
Unique ID: D000067719
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000067719
Scope Note: A component of the STAGA transcription coactivator-HAT complex that functions in Cone Rod Homeobox Protein (CRX)-dependent gene activation. It also stabilizes MICROTUBULES. CAG repeat expansion in the ATXN-7 coding region is associated with the development of SPINOCEREBELLAR ATAXIA 7.
Entry Term(s): ATXN7 Protein; Atxn-7 Protein; SCA7 Protein; Spinocerebellar Ataxia 7 Protein
Previous Indexing: Nerve Tissue Proteins (1997-2015)
See Also: Spinocerebellar Ataxias
Public MeSH Note: 2016; ATAXIN-7 was indexed under NERVE TISSUE PROTEINS 1997-2015
History Note: 2016
Date Established: 2016/01/01
Date of Entry: 2015/07/06
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000600756
Scope Note: A component of the STAGA transcription coactivator-HAT complex that functions in Cone Rod Homeobox Protein (CRX)-dependent gene activation. It also stabilizes MICROTUBULES. CAG repeat expansion in the ATXN-7 coding region is associated with the development of SPINOCEREBELLAR ATAXIA 7.
Terms: Ataxin-7 Preferred Term
Term UI T000872464
Date12/19/2014
LexicalTag NON
ThesaurusID NLM (2016); Spinocerebellar Ataxia 7 Protein
Term UI T000874001
Date01/21/2015
LexicalTag NON
ThesaurusID NLM (2016); ATXN7 Protein
Term UI T000874505
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016); Atxn-7 Protein
Term UI T000874506
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016); SCA7 Protein
Term UI T000874507
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016)

Ataxin-7 MeSH Descriptor Data 2025