MeSH Browser

MeSH Heading: Ataxin-1
Tree Number(s): D12.776.631.069.500; D12.776.660.075.500
Unique ID: D000067696
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000067696
Scope Note: A chromatin-binding factor that represses Notch signaling and associates with RNA. Expansion of the polyglutamine tract by expanded CAG repeats in the ATXN1 gene coding region is associated with SPINOCEREBELLAR ATAXIA 1.
Entry Term(s): Ataxin-1 Protein; Atxn-1 Protein; Atxn1 Protein; SCA1 Protein; Spinocerebellar Ataxia Type 1 Protein
Previous Indexing: Nerve Tissue Proteins (1995-2015); Nuclear Proteins (1995-2015)
See Also: Spinocerebellar Ataxias
Public MeSH Note: 2016; ATAXIN-1 was indexed under NERVE TISSUE PROTEINS AND NUCLEAR PROTEINS 1995-2015
History Note: 2016 (1995)
Date Established: 2016/01/01
Date of Entry: 2015/07/06
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0250931
Scope Note: A chromatin-binding factor that represses Notch signaling and associates with RNA. Expansion of the polyglutamine tract by expanded CAG repeats in the ATXN1 gene coding region is associated with SPINOCEREBELLAR ATAXIA 1.
Terms: Ataxin-1 Preferred Term
Term UI T000872352
Date12/17/2014
LexicalTag NON
ThesaurusID NLM (2016); Spinocerebellar Ataxia Type 1 Protein
Term UI T000873995
Date01/21/2015
LexicalTag ABX
ThesaurusID NLM (2016); Ataxin-1 Protein
Term UI T000874481
Date01/30/2015
LexicalTag NON
ThesaurusID NLM (2016); Atxn-1 Protein
Term UI T000874482
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016); Atxn1 Protein
Term UI T000874483
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016); SCA1 Protein
Term UI T000874484
Date01/30/2015
LexicalTag ABX
ThesaurusID NLM (2016)

Ataxin-1 MeSH Descriptor Data 2025