MeSH Browser

MeSH Heading: Patched Receptors
Tree Number(s): D12.776.543.750.058; D12.776.624.776.633
Unique ID: D000072079
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072079
Scope Note: A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.
Entry Term(s): Patched Protein; Patched Receptor; Patched Sonic Hedgehog Receptors
Public MeSH Note: 2017; PATCHED RECEPTORS was indexed under RECEPTORS, CELL SURFACE 2006-2016 and under MEMBRANE PROTEINS 1996-2005
History Note: 2017 (1996)
Date Established: 2017/01/01
Date of Entry: 2016/07/11
Revision Date: 2016/07/11

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M000616303
Scope Note: A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.
Terms: Patched Receptors Preferred Term
Term UI T000897998
Date03/31/2016
LexicalTag NON
ThesaurusID NLM (2006); Patched Receptor
Term UI T000900485
Date05/06/2016
LexicalTag NON
ThesaurusID NLM (2017); Patched Protein
Term UI T000900486
Date05/06/2016
LexicalTag NON
ThesaurusID NLM (2017); Patched Sonic Hedgehog Receptors
Term UI T000897999
Date03/31/2016
LexicalTag NON
ThesaurusID NLM (2006)

Patched Receptors MeSH Descriptor Data 2025