- Concept UI
- M0492026
- Registry Numbers
- 0
- Scope Note
- A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.
- Terms
-
Receptors, Death Domain
Preferred Term
Term UI
T659925
Date11/25/2005
LexicalTag
NON
ThesaurusID
NLM (2007)
-
Death Receptor
Term UI
T001004258
Date12/27/2019
LexicalTag
NON
ThesaurusID
NLM (2021)
-
Receptors, Death Domain Family
Term UI
T659926
Date11/25/2005
LexicalTag
NON
ThesaurusID
NLM (2007)
-
Receptors, DR Family
Term UI
T659927
Date11/25/2005
LexicalTag
ABX
ThesaurusID
NLM (2007)
-
Death Domain Receptors
Term UI
T659928
Date11/25/2005
LexicalTag
NON
ThesaurusID
NLM (2007)
-
Death Receptors
Term UI
T659929
Date11/25/2005
LexicalTag
NON
ThesaurusID
NLM (2007)