- Concept UI
- M0255479
- Registry Numbers
- 0
- Scope Note
- An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
- Terms
-
Interferon Regulatory Factor-3
Preferred Term
Term UI
T285484
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2006)
-
IRF-3 Transcription Factor
Term UI
T628476
Date01/21/2005
LexicalTag
ACX
ThesaurusID
NLM (2006)
-
IFN-Regulatory Factor 3
Term UI
T285481
Date01/01/1955
LexicalTag
ABX
ThesaurusID
NLM (2006)