MeSH Browser

MeSH Heading: GAP-43 Protein
Tree Number(s): D09.400.430.890.400; D12.776.395.550.400; D12.776.543.550.400; D12.776.631.400
Unique ID: D019922
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019922
Scope Note: A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
Entry Term(s): B-50 Protein; GAP-43; GAP43 Protein; Growth-Associated Protein 43; Nerve Growth Cone Membrane Protein GAP-43; Neuromodulin; Phosphoprotein B-50; Phosphoprotein F1; Phosphoprotein pp46
Previous Indexing: Calmodulin-Binding Proteins (1986-1992); Membrane Glycoproteins (1988-1997); Membrane Proteins (1986-1989); Nerve Tissue Proteins (1986-1997)
Public MeSH Note: 98; NERVE GROWTH CONE MEMBRANE PROTEIN GAP-43 (now GAP-43 PROTEIN) was indexed under NERVE TISSUE PROTEINS 1986-97, MEMBRANE GLYCOPROTEINS 1988-97, CALMODULIN-BINDING PROTEINS 1986-92, & MEMBRANE PROTEINS 1986-89.
History Note: 98; use GAP-43 PROTEIN (NM) 1986-97
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0029597
Scope Note: A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
Terms: GAP-43 Protein Preferred Term
Term UI T059370
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1998); Phosphoprotein B-50
Term UI T059362
Date02/25/1997
LexicalTag NON
ThesaurusID NLM (1998); GAP-43
Term UI T059364
Date02/25/1997
LexicalTag ABB
ThesaurusID NLM (1998); Neuromodulin
Term UI T059365
Date02/25/1997
LexicalTag NON
ThesaurusID NLM (1998); Phosphoprotein F1
Term UI T059366
Date02/25/1997
LexicalTag NON
ThesaurusID NLM (1998); Phosphoprotein pp46
Term UI T059367
Date02/25/1997
LexicalTag NON
ThesaurusID NLM (1998); B-50 Protein
Term UI T059368
Date02/25/1997
LexicalTag NON
ThesaurusID NLM (1998); GAP43 Protein
Term UI T059373
Date06/16/1997
LexicalTag NON
ThesaurusID NLM (1998); Nerve Growth Cone Membrane Protein GAP-43
Term UI T059361
Date03/11/1997
LexicalTag NON
ThesaurusID NLM (1998); Growth-Associated Protein 43
Term UI T362162
Date11/09/1999
LexicalTag NON
ThesaurusID NLM (2000)

GAP-43 Protein MeSH Descriptor Data 2025