MeSH Browser

MeSH Heading: CD40 Ligand
Tree Number(s): D09.400.430.890.185; D12.644.276.374.750.124; D12.776.395.550.185; D12.776.467.374.750.124; D12.776.543.550.198; D23.529.374.750.124
Unique ID: D023201
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D023201
Scope Note: A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1.
Entry Term(s): Antigen, CD154; Antigens, CD154; CD154 Antigen; CD154 Antigens; CD40L; T-B Cell Activating Molecule; TNF Superfamily, Member 5; Tumor Necrosis Factor Ligand Superfamily Member 5; gp39 Antigen, T-Cell
Previous Indexing: Membrane Glycoproteins (1992-2000)
See Also: CD40 Antigens
Public MeSH Note: 2001; CD40 LIGAND was indexed under MEMBRANE GLYCOPROTEINS 1992-2000
History Note: 2001(2000)
Date Established: 2001/01/01
Date of Entry: 2000/06/23
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0200619
Scope Note: A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1.
Terms: CD40 Ligand Preferred Term
Term UI T230624
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2001); T-B Cell Activating Molecule
Term UI T414132
Date05/12/2000
LexicalTag ABX
ThesaurusID NLM (2001); TNF Superfamily, Member 5
Term UI T660223
Date11/28/2005
LexicalTag ABX
ThesaurusID NLM (2007); Tumor Necrosis Factor Ligand Superfamily Member 5
Term UI T660370
Date11/30/2005
LexicalTag NON
ThesaurusID NLM (2007); CD154 Antigens
Term UI T230623
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2001); gp39 Antigen, T-Cell
Term UI T230629
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2001); CD40L
Term UI T230632
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2001); Antigens, CD154
Term UI T412270
Date04/21/2000
LexicalTag ABX
ThesaurusID NLM (2001); CD154 Antigen
Term UI T412272
Date04/21/2000
LexicalTag ABX
ThesaurusID NLM (2001); Antigen, CD154
Term UI T412271
Date04/21/2000
LexicalTag ABX
ThesaurusID NLM (2001)

CD40 Ligand MeSH Descriptor Data 2025