MeSH Browser

MeSH Heading: Lymphotoxin alpha1, beta2 Heterotrimer
Tree Number(s): D12.644.276.374.750.505; D12.776.467.374.750.505; D23.529.374.750.505
Unique ID: D053361
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053361
Scope Note: A heterotrimer complex consisting of one molecule of LYMPHOTOXIN-ALPHA and two molecules of the LYMPHOTOXIN-BETA. It is anchored to the cell surface via the transmembrane domains of the lymphotoxin-beta component and has specificity for the LYMPHOTOXIN BETA RECEPTOR. The lymphotoxin alpha1, beta2 heterotrimer plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER CELLS.
Entry Term(s): Lymphotoxin alpha1beta2; Lymphotoxin alphabeta; Lymphotoxin alphabeta Heterotrimer
Previous Indexing: Tumor Necrosis Factors (1974-2006)
Public MeSH Note: 2007
History Note: 2007
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2015/06/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0492829
Scope Note: A heterotrimer complex consisting of one molecule of LYMPHOTOXIN-ALPHA and two molecules of the LYMPHOTOXIN-BETA. It is anchored to the cell surface via the transmembrane domains of the lymphotoxin-beta component and has specificity for the LYMPHOTOXIN BETA RECEPTOR. The lymphotoxin alpha1, beta2 heterotrimer plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER CELLS.
Terms: Lymphotoxin alpha1, beta2 Heterotrimer Preferred Term
Term UI T662032
Date12/12/2005
LexicalTag NON
ThesaurusID NLM (2007); Lymphotoxin alpha1beta2
Term UI T662034
Date12/12/2005
LexicalTag NON
ThesaurusID NLM (2007); Lymphotoxin alphabeta
Term UI T662035
Date12/12/2005
LexicalTag NON
ThesaurusID NLM (2007); Lymphotoxin alphabeta Heterotrimer
Term UI T662033
Date12/12/2005
LexicalTag NON
ThesaurusID NLM (2007)

Lymphotoxin alpha1, beta2 Heterotrimer MeSH Descriptor Data 2025