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Lymphotoxin-alpha MeSH Descriptor Data 2025


MeSH Heading
Lymphotoxin-alpha
Tree Number(s)
D12.644.276.374.480.438
D12.644.276.374.750.500
D12.776.467.374.480.438
D12.776.467.374.750.500
D23.529.374.480.438
D23.529.374.750.500
Unique ID
D008233
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008233
Annotation
for "lymphocytotoxin" use CYTOTOXINS and LYMPHOCYTES
Scope Note
A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR.
Entry Term(s)
Lymphotoxin
Lymphotoxin-alpha3
Soluble Lymphotoxin-alpha
TNF Superfamily, Member 1
TNF-beta
Tumor Necrosis Factor Ligand Superfamily Member 1
Tumor Necrosis Factor-beta
alpha-Lymphotoxin
Public MeSH Note
2007; was LYMPHOTOXIN 1990-2006; LYMPHOTOXIN-ALPHA was indexed under LYMPHOTOXIN see LYMPHOTOXINS 1978-1989; see LYMPHOTOXIN 1974-1977; for TUMOR NECROSIS FACTOR-BETA & TNF-BETA see TUMOR NECROSIS FACTOR 1988-1989
History Note
2007 (1974-1977); for TUMOR NECROSIS FACTOR-BETA & TNF-BETA use TUMOR NECROSIS FACTOR 1988-1989
Date Established
1974/01/01
Date of Entry
1999/01/01
Revision Date
2015/06/23
Lymphotoxin-alpha Preferred
Lymphotoxin-alpha3 Narrower
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