MeSH Browser

MeSH Heading: B-Cell Activating Factor
Tree Number(s): D09.400.430.681; D12.644.276.374.750.061; D12.776.395.191; D12.776.467.374.750.061; D12.776.543.550.193; D23.529.374.750.061
Unique ID: D053264
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053264
Scope Note: A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.
Entry Term(s): Antigens, CD257; B Cell Activating Factor; B Lymphocyte Stimulator; B-Lymphocyte Activating Factor; BAFF Ligand; BLyS Protein; CD257 Antigen; CD257 Antigens; TALL-1 Protein; THANK Protein; TNF Superfamily, Member 13b; TNF and APOL-Related Leukocyte Expressed Ligand 1; TNFSF13B Protein; Tumor Necrosis Factor Ligand Superfamily Member 13b
Public MeSH Note: 2007; B-CELL ACTIVATING FACTOR was indexed under TUMOR NECROSIS FACTOR ALPHA & MEMBRANE PROTEINS 1999-2006
History Note: 2007(1999)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intercellular Signaling Peptides and Proteins [D12.644.276]
    - Cytokines [D12.644.276.374]
      - Tumor Necrosis Factors [D12.644.276.374.750]
        
        CD27 Ligand [D12.644.276.374.750.030]
        
        B-Cell Activating Factor [D12.644.276.374.750.061]
        
        4-1BB Ligand [D12.644.276.374.750.065]
        
        CD30 Ligand [D12.644.276.374.750.092]
        
        CD40 Ligand [D12.644.276.374.750.124]
        
        Cytokine TWEAK [D12.644.276.374.750.155]
        
        Ectodysplasins [D12.644.276.374.750.186]
        
        Fas Ligand Protein [D12.644.276.374.750.249]
        
        Lymphotoxin-alpha [D12.644.276.374.750.500]
        
        Lymphotoxin alpha1, beta2 Heterotrimer [D12.644.276.374.750.505]
        
        Lymphotoxin-beta [D12.644.276.374.750.515]
        
        OX40 Ligand [D12.644.276.374.750.531]
        
        RANK Ligand [D12.644.276.374.750.562]
        
        TNF-Related Apoptosis-Inducing Ligand [D12.644.276.374.750.625]
        
        Tumor Necrosis Factor-alpha [D12.644.276.374.750.626]
        
        Tumor Necrosis Factor Ligand Superfamily Member 13 [D12.644.276.374.750.656]
        
        Tumor Necrosis Factor Ligand Superfamily Member 14 [D12.644.276.374.750.690]
        
        Tumor Necrosis Factor Ligand Superfamily Member 15 [D12.644.276.374.750.720]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - Cytokines [D12.776.467.374]
      - Tumor Necrosis Factors [D12.776.467.374.750]
        
        CD27 Ligand [D12.776.467.374.750.030]
        
        B-Cell Activating Factor [D12.776.467.374.750.061]
        
        4-1BB Ligand [D12.776.467.374.750.065]
        
        CD30 Ligand [D12.776.467.374.750.092]
        
        CD40 Ligand [D12.776.467.374.750.124]
        
        Cytokine TWEAK [D12.776.467.374.750.155]
        
        Ectodysplasins [D12.776.467.374.750.186]
        
        Fas Ligand Protein [D12.776.467.374.750.249]
        
        Lymphotoxin-alpha [D12.776.467.374.750.500]
        
        Lymphotoxin alpha1, beta2 Heterotrimer [D12.776.467.374.750.505]
        
        Lymphotoxin-beta [D12.776.467.374.750.515]
        
        OX40 Ligand [D12.776.467.374.750.531]
        
        RANK Ligand [D12.776.467.374.750.562]
        
        TNF-Related Apoptosis-Inducing Ligand [D12.776.467.374.750.625]
        
        Tumor Necrosis Factor-alpha [D12.776.467.374.750.626]
        
        Tumor Necrosis Factor Ligand Superfamily Member 13 [D12.776.467.374.750.656]
        
        Tumor Necrosis Factor Ligand Superfamily Member 14 [D12.776.467.374.750.690]
        
        Tumor Necrosis Factor Ligand Superfamily Member 15 [D12.776.467.374.750.710]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]

Biological Factors [D23]
- Intercellular Signaling Peptides and Proteins [D23.529]
  - Cytokines [D23.529.374]
    - Tumor Necrosis Factors [D23.529.374.750]

B-Cell Activating Factor Preferred

Concept UI: M0305108
Scope Note: A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.
Terms: B-Cell Activating Factor Preferred Term
Term UI T662143
Date12/14/2005
LexicalTag NON
ThesaurusID NLM (2007); TALL-1 Protein
Term UI T335113
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); THANK Protein
Term UI T336237
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); BAFF Ligand
Term UI T336622
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); BLyS Protein
Term UI T364719
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); B Cell Activating Factor
Term UI T511361
Date08/12/2002
LexicalTag NON
ThesaurusID NLM (2007); B Lymphocyte Stimulator
Term UI T549657
Date08/30/2003
LexicalTag NON
ThesaurusID NLM (2007); Antigens, CD257
Term UI T660447
Date11/30/2005
LexicalTag ABX
ThesaurusID NLM (2007); TNF and APOL-Related Leukocyte Expressed Ligand 1
Term UI T660448
Date11/30/2005
LexicalTag ABX
ThesaurusID NLM (2007); TNF Superfamily, Member 13b
Term UI T660464
Date11/30/2005
LexicalTag NON
ThesaurusID NLM (2007); Tumor Necrosis Factor Ligand Superfamily Member 13b
Term UI T661547
Date12/07/2005
LexicalTag NON
ThesaurusID NLM (2007); CD257 Antigens
Term UI T661864
Date12/08/2005
LexicalTag ABX
ThesaurusID NLM (2007); CD257 Antigen
Term UI T660446
Date11/30/2005
LexicalTag ABX
ThesaurusID NLM (2007); TNFSF13B Protein
Term UI T000895153
Date02/12/2016
LexicalTag ABX
ThesaurusID NLM (2017); B-Lymphocyte Activating Factor
Term UI T664880
Date01/23/2006
LexicalTag NON
ThesaurusID NLM (2007)

B-Cell Activating Factor MeSH Descriptor Data 2025