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Asialoglycoproteins MeSH Descriptor Data 2023


MeSH Heading
Asialoglycoproteins
Tree Number(s)
D12.776.395.140
Unique ID
D001212
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001212
Scope Note
Endogenous glycoproteins from which SIALIC ACID has been removed by the action of sialidases. They bind tightly to the ASIALOGLYCOPROTEIN RECEPTOR which is located on hepatocyte plasma membranes. After internalization by adsorptive ENDOCYTOSIS they are delivered to LYSOSOMES for degradation. Therefore receptor-mediated clearance of asialoglycoproteins is an important aspect of the turnover of plasma glycoproteins. They are elevated in serum of patients with HEPATIC CIRRHOSIS or HEPATITIS.
Entry Term(s)
Asialoglycoprotein
Desialylated Glycoproteins
Registry Number
0
Previous Indexing
Glycoproteins (1966-1984)
See Also
Asialoglycoprotein Receptor
Public MeSH Note
85
History Note
85
Date Established
1985/01/01
Date of Entry
1984/05/30
Revision Date
2021/06/30
Asialoglycoproteins Preferred
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