MeSH Browser

MeSH Heading: Protein C
Tree Number(s): D08.622.705; D09.400.430.915; D12.776.124.650; D12.776.395.635; D12.776.811.243.705; D23.113.700
Unique ID: D011486
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011486
Scope Note: A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
Pharm Action: Anticoagulants
Fibrinolytic Agents
Previous Indexing: Blood Proteins (1966-1986); Glycoproteins (1966-1986)
Public MeSH Note: 87
History Note: 87
Entry Combination: deficiency:Protein C Deficiency
Date Established: 1987/01/01
Date of Entry: 1986/06/02
Revision Date: 2023/03/16

Entry Combination: deficiency:Protein C Deficiency
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Protein C MeSH Descriptor Data 2025