MeSH Browser

MeSH Heading: Clusterin
Tree Number(s): D09.400.430.750; D12.776.395.207; D12.776.580.215
Unique ID: D051152
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051152
Scope Note: A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as CANCER; APOPTOSIS; and various NEUROLOGICAL DISORDERS. Clusterin is ubiquitously expressed and appears to function as a secreted MOLECULAR CHAPERONE.
Entry Term(s): ApoJ Protein; Apolipoprotein J; Complement Lysis Inhibitor; Complement-Associated Protein SP-40,40; Ionizing Radiation-Induced Protein-8; MAC393 Antigen; SGP-2 Protein; SP 40,40 Protein; Sulfated Glycoprotein 2; Sulfated Glycoprotein-2; TRPM-2 Protein; Testosterone-Repressed Prostate Message-2 Protein; X-Ray-Inducible Protein 8; XIP8 Protein
Public MeSH Note: 2006; CLUSTERIN was indexed under GLYCOPROTEINS & MOLECULAR CHAPERONES 1981-2005, & under SALIVARY PROTEINS 1980
History Note: 2006(1980)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Molecular Chaperones [D12.776.580]

Clusterin Preferred

Concept UI: M0082230
Scope Note: A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as CANCER; APOPTOSIS; and various NEUROLOGICAL DISORDERS. Clusterin is ubiquitously expressed and appears to function as a secreted MOLECULAR CHAPERONE.
Terms: Clusterin Preferred Term
Term UI T112233
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); SP 40,40 Protein
Term UI T112217
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); Apolipoprotein J
Term UI T112222
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Complement Lysis Inhibitor
Term UI T112223
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Complement-Associated Protein SP-40,40
Term UI T112224
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Sulfated Glycoprotein 2
Term UI T112229
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Sulfated Glycoprotein-2
Term UI T112231
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); MAC393 Antigen
Term UI T112215
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); XIP8 Protein
Term UI T418027
Date06/28/2000
LexicalTag ACX
ThesaurusID NLM (2006); X-Ray-Inducible Protein 8
Term UI T555711
Date10/30/2003
LexicalTag NON
ThesaurusID NLM (2006); Testosterone-Repressed Prostate Message-2 Protein
Term UI T555712
Date10/30/2003
LexicalTag NON
ThesaurusID NLM (2006); ApoJ Protein
Term UI T628083
Date01/17/2005
LexicalTag ABX
ThesaurusID NLM (2006); TRPM-2 Protein
Term UI T628084
Date01/17/2005
LexicalTag ACX
ThesaurusID NLM (2006); SGP-2 Protein
Term UI T628085
Date01/17/2005
LexicalTag ABX
ThesaurusID NLM (2006); Ionizing Radiation-Induced Protein-8
Term UI T418026
Date06/28/2000
LexicalTag NON
ThesaurusID NLM (2006)

Clusterin MeSH Descriptor Data 2025