MeSH Browser

MeSH Heading: alpha 1-Antitrypsin
Tree Number(s): D09.400.430.594; D12.644.861.035; D12.776.124.050.070; D12.776.124.790.106.085; D12.776.377.715.085.085; D12.776.395.068; D12.776.872.035
Unique ID: D000515
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000515
Scope Note: Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.
Entry Term(s): A1PI; Prolastin; Serpin A1; Trypsin Inhibitor, alpha 1-Antitrypsin; Zemaira; alpha 1 Antiprotease; alpha 1-Antiproteinase; alpha 1-Protease Inhibitor; alpha 1-Proteinase Inhibitor
Pharm Action: Trypsin Inhibitors
Serine Proteinase Inhibitors
NLM Classification #: WH 400
See Also: alpha 1-Antitrypsin Deficiency
Public MeSH Note: 74
History Note: 74
Entry Combination: deficiency:alpha 1-Antitrypsin Deficiency
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2023/03/16

Entry Combination: deficiency:alpha 1-Antitrypsin Deficiency
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0000780
Scope Note: Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.
Terms: alpha 1-Antitrypsin Preferred Term
Term UI T001523
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1974); alpha 1-Protease Inhibitor
Term UI T001524
Date04/26/1989
LexicalTag NON
ThesaurusID NLM (1990); Trypsin Inhibitor, alpha 1-Antitrypsin
Term UI T001525
Date04/01/1977
LexicalTag NON
ThesaurusID UNK (19XX); alpha 1 Antiprotease
Term UI T001526
Date09/18/1981
LexicalTag NON
ThesaurusID UNK (19XX); alpha 1-Proteinase Inhibitor
Term UI T001527
Date04/26/1989
LexicalTag NON
ThesaurusID NLM (1990); A1PI
Term UI T001528
Date03/11/1997
LexicalTag ABB
ThesaurusID NLM (1998); alpha 1-Antiproteinase
Term UI T001522
Date11/02/1988
LexicalTag NON
ThesaurusID UNK (19XX); Serpin A1
Term UI T734758
Date02/09/2009
LexicalTag NON
ThesaurusID NLM (2010)

alpha 1-Antitrypsin MeSH Descriptor Data 2025