MeSH Browser

MeSH Heading: alpha-2-Antiplasmin
Tree Number(s): D09.400.430.610; D12.644.861.050; D12.776.124.790.106.090; D12.776.377.715.085.090; D12.776.395.080; D12.776.872.050
Unique ID: D000979
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000979
Scope Note: A member of the serpin superfamily found in plasma that inhibits the lysis of fibrin clots which are induced by plasminogen activator. It is a glycoprotein, molecular weight approximately 70,000 that migrates in the alpha 2 region in immunoelectrophoresis. It is the principal plasmin inactivator in blood, rapidly forming a very stable complex with plasmin.
Entry Term(s): Serpin F2; alpha 2-Plasmin Inhibitor; alpha(2)-Plasmin Inhibitor; alpha-2 Antiplasmin
Pharm Action: Antifibrinolytic Agents
Serine Proteinase Inhibitors
Previous Indexing: Fibrinolysin/antagonists & inhibitors (1968-1979)
Public MeSH Note: 2010; see ANTIPLASMIN 1980-2009
History Note: 2010(1980)
Date Established: 1980/01/01
Date of Entry: 1979/05/23
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0001495
Scope Note: A member of the serpin superfamily found in plasma that inhibits the lysis of fibrin clots which are induced by plasminogen activator. It is a glycoprotein, molecular weight approximately 70,000 that migrates in the alpha 2 region in immunoelectrophoresis. It is the principal plasmin inactivator in blood, rapidly forming a very stable complex with plasmin.
Terms: alpha-2-Antiplasmin Preferred Term
Term UI T358821
Date11/08/1999
LexicalTag NON
ThesaurusID NLM (2000); alpha-2 Antiplasmin
Term UI T003020
Date06/04/1981
LexicalTag NON
ThesaurusID UNK (19XX); Serpin F2
Term UI T734764
Date02/09/2009
LexicalTag NON
ThesaurusID NLM (2010); alpha(2)-Plasmin Inhibitor
Term UI T003018
Date09/18/1980
LexicalTag NON
ThesaurusID UNK (19XX); alpha 2-Plasmin Inhibitor
Term UI T003019
Date05/23/1979
LexicalTag NON
ThesaurusID UNK (19XX)

alpha-2-Antiplasmin MeSH Descriptor Data 2025