MeSH Browser

MeSH Heading: Serpins
Tree Number(s): D12.644.861; D12.776.872; D27.505.519.389.745.800.675
Unique ID: D015843
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015843
Scope Note: A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
Entry Term(s): Serpin; Serpin Peptidase Inhibitors; Serpin Protease Inhibitors; Serpin Superfamily
NLM Classification #: QU 143
Previous Indexing: Enzyme Inhibitors (1968-1978); Protease Inhibitors (1979-1989)
Public MeSH Note: 90
History Note: 90
Date Established: 1990/01/01
Date of Entry: 1989/05/26
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024262
Scope Note: A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
Terms: Serpins Preferred Term
Term UI T046974
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990); Serpin
Term UI T000996408
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); Serpin Protease Inhibitors
Term UI T000914710
Date01/25/2017
LexicalTag NON
ThesaurusID NLM (2018); Serpin Peptidase Inhibitors
Term UI T000914711
Date01/25/2017
LexicalTag NON
ThesaurusID NLM (2018)

Serpins MeSH Descriptor Data 2025