MeSH Browser

MeSH Heading: Protein Isoforms
Tree Number(s): D12.776.800
Unique ID: D020033
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020033
Annotation: IM general only; coordinate NIM with specific protein (IM); for enzymes use ISOENZYMES
Scope Note: Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
Entry Term(s): Isoform; Isoforms; Protein Isoform; Protein Splice Variant; Protein Splice Variants; Splice Variants, Protein
See Also: Alternative Splicing; RNA Splice Sites
Public MeSH Note: 1999
History Note: 1999
Date Established: 1999/01/01
Date of Entry: 2024/08/09
Revision Date: 2024/05/22

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0029740
Scope Note: Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
Terms: Protein Isoforms Preferred Term
Term UI T059681
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1999); Isoform
Term UI T000997879
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Isoforms
Term UI T059680
Date01/14/1998
LexicalTag NON
ThesaurusID NLM (1999); Protein Isoform
Term UI T000997878
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021)

Protein Isoforms MeSH Descriptor Data 2025