- Concept UI
- M0093656
- Registry Number
- 0
- Scope Note
- Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
- Terms
-
Antimicrobial Cationic Peptides
Preferred Term
Term UI
T123651
LexicalTag
NON
ThesaurusID
NLM (2001)
-
Microbicidal Cationic Proteins
Term UI
T123659
LexicalTag
NON
ThesaurusID
NLM (2001)
-
Cationic Antimicrobial Peptides
Term UI
T693817
Date03/16/2007
LexicalTag
NON
ThesaurusID
NLM (2008)
-
Host Defense Peptide
Term UI
T000996500
Date11/15/2019
LexicalTag
NON
ThesaurusID
NLM (2021)
-
Host Defense Peptides
Term UI
T000945353
Date07/30/2018
LexicalTag
NON
ThesaurusID
NLM (2020)