MeSH Browser

MeSH Heading: Antimicrobial Cationic Peptides
Tree Number(s): D12.644.050; D12.644.066.500; D12.776.543.695.054
Unique ID: D023181
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D023181
Scope Note: Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Entry Term(s): Amphipathic Cationic Antimicrobial Peptides; Cationic Antimicrobial Peptide; Cationic Antimicrobial Peptides; Cationic Host Defense Peptides; Host Defense Peptide; Host Defense Peptides; Microbicidal Cationic Proteins
Pharm Action: Anti-Infective Agents
Registry Numbers: 0
Previous Indexing: Proteins (1981-2000)
See Also: Blood Bactericidal Activity
Public MeSH Note: 2001; MICROBICIDAL CATIONIC PROTEINS (now ANTIMICROBIAL CATIONIC PEPTIDES) was indexed under PROTEINS 1981-2000
History Note: 2001; use ANTIMICROBIAL CATIONIC PEPTIDES (NM) to search MICROBICIDAL CATIONIC PROTEINS 1981-2000
Date Established: 2001/01/01
Date of Entry: 2000/06/21
Revision Date: 2021/05/10

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0093656
Registry Numbers: 0
Scope Note: Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Terms: Antimicrobial Cationic Peptides Preferred Term
Term UI T123651
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2001); Cationic Host Defense Peptides
Term UI T001102469
Date03/15/2021
LexicalTag NON
ThesaurusID NLM (2022); Cationic Antimicrobial Peptide
Term UI T001087309
Date08/24/2020
LexicalTag NON
ThesaurusID NLM (2022); Cationic Antimicrobial Peptides
Term UI T693817
Date03/16/2007
LexicalTag NON
ThesaurusID NLM (2008); Microbicidal Cationic Proteins
Term UI T123659
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2001)

Antimicrobial Cationic Peptides MeSH Descriptor Data 2024