MeSH Browser

MeSH Heading: Antimicrobial Cationic Peptides
Tree Number(s): D12.644.050; D12.776.543.695.054
Unique ID: D023181
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D023181
Scope Note: Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Entry Term(s): Amphipathic Cationic Antimicrobial Peptides; Cationic Antimicrobial Peptides; Host Defense Peptide; Host Defense Peptides; Microbicidal Cationic Proteins
Pharm Action: Anti-Infective Agents
Registry Number: 0
Previous Indexing: Proteins (1981-2000)
See Also: Blood Bactericidal Activity
Public MeSH Note: 2001; MICROBICIDAL CATIONIC PROTEINS (now ANTIMICROBIAL CATIONIC PEPTIDES) was indexed under PROTEINS 1981-2000
History Note: 2001; use ANTIMICROBIAL CATIONIC PEPTIDES (NM) to search MICROBICIDAL CATIONIC PROTEINS 1981-2000
Date Established: 2001/01/01
Date of Entry: 2000/06/21
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0093656
Registry Number: 0
Scope Note: Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Terms: Antimicrobial Cationic Peptides Preferred Term
Term UI T123651
LexicalTag NON
ThesaurusID NLM (2001); Microbicidal Cationic Proteins
Term UI T123659
LexicalTag NON
ThesaurusID NLM (2001); Cationic Antimicrobial Peptides
Term UI T693817
Date03/16/2007
LexicalTag NON
ThesaurusID NLM (2008); Host Defense Peptide
Term UI T000996500
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Host Defense Peptides
Term UI T000945353
Date07/30/2018
LexicalTag NON
ThesaurusID NLM (2020)

Antimicrobial Cationic Peptides MeSH Descriptor Data 2021