MeSH Browser

MeSH Heading: Hepcidins
Tree Number(s): D12.776.494.249; D12.776.543.695.054.425
Unique ID: D064451
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064451
Scope Note: Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity.
Entry Term(s): Hepcidin; Liver-Expressed Antimicrobial Peptide; Pro-Hepcidin; Prohepcidin
Pharm Action: Anti-Infective Agents
Registry Number: 0
Previous Indexing: Antimicrobial Cationic Peptides (2013)
See Also: Anemia; Hemochromatosis
Public MeSH Note: 2014
History Note: 2014
Date Established: 2014/01/01
Date of Entry: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0581933
Registry Number: 0
Scope Note: Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity.
Terms: Hepcidins Preferred Term
Term UI T838255
Date03/07/2013
LexicalTag NON
ThesaurusID NLM (2014); Liver-Expressed Antimicrobial Peptide
Term UI T838259
Date03/07/2013
LexicalTag NON
ThesaurusID NLM (2014); Hepcidin
Term UI T838258
Date03/07/2013
LexicalTag NON
ThesaurusID NLM (2014)

Hepcidins MeSH Descriptor Data 2023