NLM Logo

Exenatide MeSH Descriptor Data 2021


MeSH Heading
Exenatide
Tree Number(s)
D12.644.187
D20.888.300
D23.946.833.300
Unique ID
D000077270
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077270
Scope Note
A synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the Gila monster lizard (Heloderma suspectum). Exenatide increases CYCLIC AMP levels in pancreatic acinar cells and acts as a GLUCAGON-LIKE PEPTIDE-1 RECEPTOR (GLP-1) agonist and incretin mimetic, enhancing insulin secretion in response to increased glucose levels; it also suppresses inappropriate glucagon secretion and slows gastric emptying. It is used an anti-diabetic and anti-obesity agent.
Entry Term(s)
AC 2993
AC 2993 LAR
Bydureon
Byetta
Ex4 Peptide
Exendin 4
Exendin-4
ITCA 650
Pharm Action
Hypoglycemic Agents
Anti-Obesity Agents
Incretins
Registry Number
9P1872D4OL
Related Numbers
141732-76-5
Public MeSH Note
2019; EXENATIDE was indexed under PEPTIDES and VENOMS 1992-2018
History Note
2019 (1992)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/06/19
Exenatide Preferred
Bydureon Narrower
ITCA 650 Narrower
AC 2993 LAR Narrower
Exendin-4 Broader
Byetta Narrower
AC 2993 Narrower
page delivered in 0.197s