MeSH Browser

MeSH Heading: Antithrombins
Tree Number(s): D27.505.519.389.745.800.449; D27.505.954.502.119.500
Unique ID: D000991
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000991
Annotation: ANTITHROMBIN PROTEINS is also available
Scope Note: Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.
Entry Term(s): Antithrombin; Direct Antithrombin; Direct Antithrombins; Direct Thrombin Inhibitor; Direct Thrombin Inhibitors
NLM Classification #: QV 193
Public MeSH Note: see ANTITHROMBIN 1964-1966
History Note: 2011(1964)
Date Established: 1967/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0544738
Scope Note: Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.
Terms: Antithrombins Preferred Term
Term UI T768749
Date04/06/2010
LexicalTag NON
ThesaurusID NLM (2011); Direct Thrombin Inhibitor
Term UI T000996977
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021); Antithrombin
Term UI T000996332
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); Direct Antithrombins
Term UI T768209
Date03/30/2010
LexicalTag NON
ThesaurusID NLM (2011); Direct Thrombin Inhibitors
Term UI T767856
Date03/24/2010
LexicalTag NON
ThesaurusID NLM (2011); Direct Antithrombin
Term UI T000996978
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021)

Antithrombins MeSH Descriptor Data 2025