MeSH Browser

MeSH Heading: Pigment Epithelium-Derived Factor
Tree Number(s): D12.644.276.860.831; D12.644.861.001; D12.776.306.608; D12.776.467.860.831; D12.776.631.600.831; D12.776.872.001; D23.529.850.831
Unique ID: D000099174
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000099174
Scope Note: A neurotrophic protein and serpin that induces CELL DIFFERENTIATION in RETINOBLASTOMA cells and also functions as an ANGIOGENESIS INHIBITOR in the mammalian eye.
Entry Term(s): Early PDL Protein; Early Population Doubling Level Cdna-1 ProteinEarly Population Doubling Level Cdna-1 Protein; Early Population Doubling Level Protein; SERPIN-F1; SERPINF1
Registry Numbers: KVT56XP92G
Public MeSH Note: 2026 (1993)
History Note: 2026; PIGMENT EPITHELIUM-DERIVED FACTOR was indexed under EYE PROTEINS, NERVE GROWTH FACTORS, and SERPINS 1994-2025, and under PROTEINS 1993
Date Introduced: 2026/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Pigment Epithelium-Derived Factor MeSH Descriptor Data 2026