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Retinoblastoma MeSH Descriptor Data 2023


MeSH Heading
Retinoblastoma
Tree Number(s)
C04.557.465.625.600.725
C04.557.470.670.725
C04.557.580.625.600.725
C04.588.364.818.760
C11.270.862
C11.319.475.760
C11.768.717.760
Unique ID
D012175
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D012175
Annotation
coordinate IM with RETINAL NEOPLASMS (IM); /‌genetics: consider also GENES, RETINOBLASTOMA
Scope Note
A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
Entry Term(s)
Eye Cancer, Retinoblastoma
Familial Retinoblastoma
Glioblastoma, Retinal
Glioma, Retinal
Hereditary Retinoblastoma
Neuroblastoma, Retinal
Sporadic Retinoblastoma
NLM Classification #
WW 270
See Also
Genes, Retinoblastoma
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2018/06/15
Retinoblastoma Preferred
Sporadic Retinoblastoma Narrower
Familial Retinoblastoma Narrower
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