MeSH Browser

MeSH Heading: Genes, Retinoblastoma
Tree Number(s): G05.360.340.024.340.375.249.400; G05.360.340.024.340.415.400.400
Unique ID: D016161
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016161
Scope Note: Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.
Entry Term(s): Genes, Rb; Rb Genes; Retinoblastoma Genes
NLM Classification #: QZ 210
Previous Indexing: Retinoblastoma/genetics (1972-1990)
See Also: Retinoblastoma
Public MeSH Note: 91
History Note: 91
Date Established: 1991/01/01
Date of Entry: 1990/05/07
Revision Date: 2010/06/25

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0024674
Scope Note: Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.
Terms: Genes, Retinoblastoma Preferred Term
Term UI T047989
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1991); Genes, Rb
Term UI T047990
Date02/01/1990
LexicalTag NON
ThesaurusID NLM (1991); Rb Genes
Term UI T047991
Date05/03/1990
LexicalTag NON
ThesaurusID NLM (1991); Retinoblastoma Genes
Term UI T047988
Date04/16/1990
LexicalTag NON
ThesaurusID NLM (1991)

Genes, Retinoblastoma MeSH Descriptor Data 2025