MeSH Browser

MeSH Heading: Genes, p16
Tree Number(s): G05.360.340.024.340.375.249.375; G05.360.340.024.340.415.400.375
Unique ID: D019942
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019942
Scope Note: Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (From Segen, Current Med Talk, 1995) Two alternatively spliced gene products are encoded by p16: CYCLIN-DEPENDENT KINASE INHIBITOR P16 and TUMOR SUPPRESSOR PROTEIN P14ARF.
Entry Term(s): CDKN2 Genes; Genes, CDKN2; Genes, CDKN2A; Genes, MTS1; Genes, p16INK4; Genes, p16INK4A; MTS1 Genes; p16 Genes; p16INK4 Genes
Previous Indexing: Genes, Suppressor, Tumor (1994-1997)
See Also: Cyclin-Dependent Kinase Inhibitor p16; Tumor Suppressor Protein p14ARF
Public MeSH Note: 98
History Note: 98
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2008/07/08

Allowable Qualifiers: drug effects (DE)

ethics (ES)

physiology (PH)

radiation effects (RE)

Concept UI: M0029616
Scope Note: Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (From Segen, Current Med Talk, 1995) Two alternatively spliced gene products are encoded by p16: CYCLIN-DEPENDENT KINASE INHIBITOR P16 and TUMOR SUPPRESSOR PROTEIN P14ARF.
Terms: Genes, p16 Preferred Term
Term UI T059436
Date01/01/1999
LexicalTag ABX
ThesaurusID NLM (1998); Genes, p16INK4
Term UI T059437
Date02/28/1997
LexicalTag NON
ThesaurusID NLM (1998); p16INK4 Genes
Term UI T059438
Date02/28/1997
LexicalTag NON
ThesaurusID NLM (1998); Genes, p16INK4A
Term UI T059439
Date02/28/1997
LexicalTag NON
ThesaurusID NLM (1998); CDKN2 Genes
Term UI T059430
Date02/28/1997
LexicalTag NON
ThesaurusID NLM (1998); Genes, CDKN2
Term UI T059431
Date02/28/1997
LexicalTag NON
ThesaurusID NLM (1998); Genes, CDKN2A
Term UI T059432
Date02/28/1997
LexicalTag NON
ThesaurusID NLM (1998); Genes, MTS1
Term UI T059433
Date02/28/1997
LexicalTag NON
ThesaurusID NLM (1998); p16 Genes
Term UI T059435
Date02/28/1997
LexicalTag NON
ThesaurusID NLM (1998); MTS1 Genes
Term UI T059434
Date02/28/1997
LexicalTag NON
ThesaurusID NLM (1998)

Genes, p16 MeSH Descriptor Data 2025