MeSH Browser

MeSH Heading: Genes, Tumor Suppressor
Tree Number(s): G05.360.340.024.340.375.249; G05.360.340.024.340.415.400
Unique ID: D016147
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016147
Annotation: Manual 24.4.4.3
Scope Note: Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
Entry Term(s): Anti-Oncogenes; Antioncogenes; Cancer Suppressor Genes; Emerogenes; Genes, Cancer Suppressor; Genes, Growth Suppressor; Genes, Metastasis Suppressor; Genes, Onco-Suppressor; Growth Suppressor Genes; Metastasis Suppressor Genes; Oncogenes, Recessive; Tumor Suppressing Genes; Tumor Suppressor Genes
NLM Classification #: QZ 210
Previous Indexing: Suppression, Genetic (1986-1990)
See Also: Tumor Suppressor Proteins
Public MeSH Note: 2002; see GENES, SUPPRESSOR, TUMOR 1991-2001
History Note: 2002 (1991)
Date Established: 1991/01/01
Date of Entry: 1990/05/07
Revision Date: 2008/07/08

Allowable Qualifiers: drug effects (DE)

ethics (ES)

physiology (PH)

radiation effects (RE)

Concept UI: M0024663
Scope Note: Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
Terms: Genes, Tumor Suppressor Preferred Term
Term UI T047960
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1991); Antioncogenes
Term UI T047956
Date01/29/1990
LexicalTag NON
ThesaurusID NLM (1991); Emerogenes
Term UI T047957
Date01/29/1990
LexicalTag NON
ThesaurusID NLM (1991); Genes, Onco-Suppressor
Term UI T047958
Date01/31/1990
LexicalTag NON
ThesaurusID NLM (1991); Cancer Suppressor Genes
Term UI T427982
Date11/03/2000
LexicalTag NON
ThesaurusID NLM (2002); Oncogenes, Recessive
Term UI T047961
Date01/30/1990
LexicalTag NON
ThesaurusID NLM (1991); Anti-Oncogenes
Term UI T047962
Date01/29/1990
LexicalTag NON
ThesaurusID NLM (1991); Tumor Suppressing Genes
Term UI T047963
Date01/29/1990
LexicalTag NON
ThesaurusID NLM (1991); Genes, Cancer Suppressor
Term UI T427990
Date11/03/2000
LexicalTag NON
ThesaurusID NLM (2002); Tumor Suppressor Genes
Term UI T047959
Date01/29/1990
LexicalTag NON
ThesaurusID NLM (1991)

Genes, Tumor Suppressor MeSH Descriptor Data 2023