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Genes, BRCA1 MeSH Descriptor Data 2025


MeSH Heading
Genes, BRCA1
Tree Number(s)
G05.360.340.024.340.375.249.100
G05.360.340.024.340.415.400.100
Unique ID
D019398
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019398
Annotation
BRCA stands for "BReast CAncer"
Scope Note
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human CHROMOSOME 17 at locus 17q21. Mutations of this gene are associated with the formation of HEREDITARY BREAST AND OVARIAN CANCER SYNDROME. It encodes a large nuclear protein that is a component of DNA repair pathways.
Entry Term(s)
BRCA1 Gene
Previous Indexing
Genes, Suppressor, Tumor (1993-1996)
See Also
BRCA1 Protein
Public MeSH Note
97
History Note
97
Date Established
1997/01/01
Date of Entry
1996/06/10
Revision Date
2014/06/06
Genes, BRCA1 Preferred
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