MeSH Browser

MeSH Heading: Connexin 50
Tree Number(s): D12.776.306.297; D12.776.543.585.250.250
Unique ID: D000099264
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000099264
Scope Note: A connexin which forms the structural component of GAP JUNCTIONS in the EYE LENS. In humans, variants in the GJA8 gene cause multiple types of CATARACT.
Entry Term(s): Gap Junction Protein Cx50; Lens Intrinsic Protein MP 70; Lens Protein MP70
Public MeSH Note: 2026; CONNEXIN 50 was indexed under CONNEXINS 1987-2025
History Note: 2026 (1987)
Date Introduced: 2026/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000769069
Scope Note: A connexin which forms the structural component of GAP JUNCTIONS in the EYE LENS. In humans, variants in the GJA8 gene cause multiple types of CATARACT.
Terms: Connexin 50 Preferred Term
Term UI T001148645
Date05/22/2025
LexicalTag NON
ThesaurusID NLM (1987); Gap Junction Protein Cx50
Term UI T001148646
Date05/22/2025
LexicalTag ABX
ThesaurusID NLM (1987); Lens Intrinsic Protein MP 70
Term UI T001148647
Date05/22/2025
LexicalTag ABX
ThesaurusID NLM (1987); Lens Protein MP70
Term UI T001148648
Date05/22/2025
LexicalTag ABX
ThesaurusID NLM (1987)

Connexin 50 MeSH Descriptor Data 2026