MeSH Browser

MeSH Heading: Connexins
Tree Number(s): D12.776.543.585.250
Unique ID: D017630
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017630
Scope Note: A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
Entry Term(s): Connexin; Connexin Complex Proteins; Gap Junction Channel Proteins; Gap Junction Protein; Gap Junction Proteins
Previous Indexing: Membrane Proteins (1981-1993)
See Also: Erythrokeratodermia Variabilis
Public MeSH Note: 94; GAP JUNCTION PROTEIN was indexed under MEMBRANE PROTEINS 1982-93
Online Note: use CONNEXINS (NM) to search GAP JUNCTION PROTEIN 1982-93
History Note: 94; GAP JUNCTION PROTEIN was (NM) 1982-93
Date Established: 1994/01/01
Date of Entry: 1993/08/06
Revision Date: 2023/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0026696
Scope Note: A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
Terms: Connexins Preferred Term
Term UI T052822
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1994); Connexin
Term UI T000999743
Date11/29/2019
LexicalTag NON
ThesaurusID NLM (2021); Gap Junction Channel Proteins
Term UI T691757
Date02/15/2007
LexicalTag NON
ThesaurusID NLM (2008); Gap Junction Protein
Term UI T052820
Date12/23/1992
LexicalTag NON
ThesaurusID NLM (1994); Gap Junction Proteins
Term UI T052821
Date07/09/1992
LexicalTag NON
ThesaurusID NLM (1993); Connexin Complex Proteins
Term UI T001135666
Date03/30/2023
LexicalTag NON
ThesaurusID NLM (2024)

Connexins MeSH Descriptor Data 2025