MeSH Browser

MeSH Heading: Ion Channels
Tree Number(s): D12.776.157.530.400; D12.776.543.550.450; D12.776.543.585.400
Unique ID: D007473
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007473
Annotation: general or unspecified; prefer specifics; coordinate IM with specific ion / metab (IM)
Scope Note: Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.
Entry Term(s): Ion Channel; Ionic Channel; Ionic Channels; Membrane Channel; Membrane Channels
NLM Classification #: QU 55.7
Previous Indexing: Cell Membrane (1966-1978); Electric Conductivity (1968-1978); Membrane Potentials (1967-1978)
See Also: Ion Channel Gating; Ion Pumps
Public MeSH Note: 79
History Note: 79
Date Established: 1979/01/01
Date of Entry: 1978/05/19
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0011674
Scope Note: Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.
Terms: Ion Channels Preferred Term
Term UI T022459
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1979); Ion Channel
Term UI T022458
Date02/17/1993
LexicalTag NON
ThesaurusID NLM (1994); Membrane Channel
Term UI T022460
Date02/17/1993
LexicalTag NON
ThesaurusID NLM (1994); Membrane Channels
Term UI T022461
Date05/19/1978
LexicalTag NON
ThesaurusID UNK (19XX); Ionic Channel
Term UI T022462
Date10/12/1989
LexicalTag NON
ThesaurusID NLM (1991); Ionic Channels
Term UI T022463
Date02/17/1993
LexicalTag NON
ThesaurusID NLM (1994)

Ion Channels MeSH Descriptor Data 2025